System76 is built on web technologies written in JavaScript.

Your browser currently has JavaScript disabled. Some pages and features will not work as intended.

System76 is built on web technologies your browser doesn't support.

If you have questions about an order, or require support, feel free to contact us.


Thelio Mega is the world's smallest and quietest quad-GPU workstation for deep learning and scientific computing. We've engineered the system to ensure your top-line components perform to their fullest potential.

  • Quad-GPU Compute Workstation
  • Threadripper PRO 5000 WX-Series Processors
  • Up to 512 GB of ECC memory
  • PCIe 4.0 NVMe Storage
Hero thumbnail background image
System76 Thelio Major with Walnut Accent
  • Quad-GPU Compute Workstation
  • Threadripper PRO 5000 WX-Series Processors
  • Up to 512 GB of ECC memory
  • PCIe 4.0 NVMe Storage
Detail of the machine exterior showing the 3-Body Problem intake vent, featuring the walnut accent.


Thelio Mega’s thermals are actually two separate systems, as we found it more effective to divide and conquer. Unique airflows keep heat generated by the CPU and GPU from mixing, exhaust air effectively, and prevent throttling.


Full-Core GPU Compute

Heat builds up quickly when you have up to 4 NVIDIA RTX or AMD Radeon Pro GPUs stacked atop one another. Rather than use a single vent to cool the entire system, intake fans on the bottom and side panels blow cool air directly onto your GPUs. Everything down to the GPU brace has been tested for maximum thermal efficiency. The result is consistent access to every last core of performance in your system.

Open Bench CPU Performance

Meanwhile, a separate duct isolates the airflow to your CPU. A dedicated intake vent on the side panel directs cool air towards the heat sink. In what’s called a closed-loop phase change, actuating fluid evaporates into a gas, drawing thermal energy away from the CPU and towards the heat sink. Here, it is cooled into a liquid and returned to the transfer plate. The hot air then exits via the exhaust port. The process yields performance similar to if your components were sitting on a test bench.

Quiet, Adaptive Cooling

We tested a wide variety of fan sizes and alignments until we arrived at the most effective solution. Large 140mm fans move air more effectively at a lower RPM, producing quieter acoustics. The Thelio IO board allows your operating system to monitor the temperature of your GPUs and adjust fan speeds for intensive computing.


Seconds add up quickly when working with large datasets. Thelio Mega is equipped with high-performance components to save you time on reaching your next discovery.


Up to 4 NVIDIA A-series or AMD Radeon Pro GPUs

NVIDIA A-series and AMD Radeon Pro GPUs use ECC memory to reliably process tasks at rapid speeds. NVIDIA-exclusive CUDA and Tensorflow tools thrive at high core counts, needing only a single line of code to install on Pop!_OS.

Up to 128 CPU Threads

Multitasking is key. AMD Ryzen Threadripper Pro 5000 Series processors provide the greatest performance for workstations while supporting your graphics cards with up to 128 CPU threads.

Long-Term Storage

Up to 24TB of fast PCIe 4 M.2 NVMe storage. Up to 32TB additional SSD storage on hot swappable 2.5" drives. Cooled aluminum drive cages keep your drives performant, while rubber stoppers mute noisy vibrations. Expandable storage lets your system grow with you from project to groundbreaking project.

Cloud-Friendly Network Connection

Transfer data between devices at breakneck speeds. Dual 10GB Ethernet Ports operate at speeds 10 times faster than a standard Ethernet connection.


Thelio desktops are designed to provide easy access to your motherboard for upgrades and repairs. Slip in drives, add memory, and upgrade graphics cards at will with our open hardware design.


Side Panel Access

Unplug your ducts and access everything in the system. No obstructive wires, no loose parts.

Pre-Wired for Upgrades

Any wires you’ll ever need are already provided inside the system. To level up your graphics power, simply plug in your new GPU and fire up those CUDA Cores.

Never Lose Screws Again

The screw bay on the GPU cooling panel houses enough screws to install the maximum number of 2.5” storage SSDs. They will be with you, always.


Rigid aluminum is cut, powder coated, and molded into a light, durable chassis. From the the Solar System exhaust commemorating the Unix epoch to its arcade-style power button, Thelio Mega adds elegance and character to your workplace.

Detail of the machine exterior showing the 3-Body Problem intake vent.
Detail of the machine interior showing storage drive inside the aluminum cage.
Detail of the machine exterior showing geometric etching of mountains.
Detail of the aluminum chassis without any components installed.
Detail of the exterior showing combination of wood accent and powder-coated aluminum.
Detail of the interior showing System76 logo punched on the metal screw cover.
Detail of the exterior showing artful intake vent with holes shaped as rockets.
Detail of the interior showing large CPU cooling duct.


Save 12% on a fully customizable System76 keyboard when you configure your system with the portable Launch Lite, Launch with high-speed USB hub, or Launch Heavy with hub and NumPad.

Learn more about Launch keyboards >

Launch and Launch Lite keyboards
Thelio Mega with Walnut accent
Walnut accentbirch accentred accentBlue accentpink accenttraces accent

Thelio Mega


Tech Specs

Operating System

Pop!_OS 22.04 LTS or Ubuntu 22.04 LTS


AMD Ryzen™ Threadripper™ PRO 5000 WX-Series


Up to 4 x NVIDIA® Graphics or AMD Radeon Pro GPUs

Video Ports

Options are dependent on graphics selection. Most include 3x DisplayPort, 1x HDMI port.


Up to 512GB Octa Channel ECC DDR4 @ 3200 MHz


Up to 48 TB, 2 x PCIe Gen 4 NVMe, 4 x 2.5" SATA drives

Rear Ports

1 x USB 3.2 Gen 2x2 port (USB Type-C), 9 x USB 3.2 Gen 2 ports (8 x Type-A, 1 x USB Type-C), 1 x BIOS FlashBack™  button, 1 x Clear CMOS button

Rear Audio

5 × Audio Jacks, 1 x Optical S/PDIF out port


2 x Intel® X550-AT2 dual 10Gb Ethernet ports, Wi-Fi 6 (802.11 a/b/g/n/ac/ax) Bluetooth 5.2

Power Supply

1650 Watt 80+ Gold Certified


18.82″ × 10.35″ × 17.24″ (478 × 263 × 438mm)